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1

Status of acute systemic toxicity testing requirements and data uses by U.S. regulatory agencies

Strickland, Judy, Clippinger, Amy J., Brown, Jeffrey, Allen, David, Jacobs, Abigail, Matheson, Joanna, Lowit, Anna, Reinke, Emily N., Johnson, Mark S., Quinn, Michael J., Mattie, David, Fitzpatrick, S

Journal:

Regulatory Toxicology and Pharmacology

Year:

2018

Language:

english

File:

PDF, 355 KB

english, 2018

2

Modulation of Apoptotic Signaling by the Hepatitis B Virus X Protein

Rawat, Siddhartha, Clippinger, Amy, Bouchard, Michael

Journal:

Year:

2012

Language:

english

File:

PDF, 709 KB

english, 2012

3

Predicting pulmonary fibrosis in humans after exposure to multi-walled carbon nanotubes (MWCNTs)

Sharma, Monita, Nikota, Jake, Halappanavar, Sabina, Castranova, Vincent, Rothen-Rutishauser, Barbara, Clippinger, Amy J.

Journal:

Archives of Toxicology

Year:

2016

Language:

english

File:

PDF, 1.22 MB

english, 2016

4

Evaluation of the avian acute oral and sub-acute dietary toxicity test for pesticide registration

Hilton, Gina M., Odenkirchen, Edward, Panger, Melissa, Waleko, Garland, Lowit, Anna, Clippinger, Amy J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.51 MB

english, 2019

5

Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy

Amy K. Clippinger, Simon D’Alton, Wen-Lang Lin, Tania F. Gendron…

Journal:

Acta Neuropathologica

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

6

A comparison of suspension versus air–liquid interface experiments to assess the (pro-)fibrotic potential of carbon nanotubes in vitro

Barosova, Hana, Chortarea, Savvina, Septiadi, Dedy, Sharma, Monita, Clippinger, Amy J., Zerimariam, Fikad, Petri-Fink, Alke, Rothen-Rutishauser, Barbara

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 55 KB

english, 2017

7

Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing

Hamm, Jon, Sullivan, Kristie, Clippinger, Amy J., Strickland, Judy, Bell, Shannon, Bhhatarai, Barun, Blaauboer, Bas, Casey, Warren, Dorman, David, Forsby, Anna, Garcia-Reyero, Natàlia, Gehen, Sean, Gr

Journal:

Toxicology in Vitro

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

8

Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection

Yongjun Yu, Amy J. Clippinger, James C. Alwine

Journal:

Trends in Microbiology

Year:

2011

Language:

english

File:

PDF, 597 KB

english, 2011

9

Framework to Evaluate Exposure Relevance and Data Needs for Risk Assessment of Nanomaterials using in Vitro Testing Strategies

Sharma, Monita, Shatkin, Jo Anne, Cairns, Carolyn, Canady, Richard, Clippinger, Amy J.

Journal:

Year:

2016

Language:

english

File:

PDF, 447 KB

english, 2016

10

Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements

Melbourne, Jodie, Sharma, Monita, Allen, David, Clippinger, Amy

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 57 KB

english, 2017

11

Aerosol generation and characterization of multi-walled carbon nanotubes exposed to cells cultured at the air-liquid interface

Polk, William W., Sharma, Monita, Sayes, Christie M., Hotchkiss, Jon A., Clippinger, Amy J.

Journal:

Particle and Fibre Toxicology

Year:

2015

Language:

english

File:

PDF, 935 KB

english, 2015

12

Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multi-Walled Carbon Nanotubes

Barosova, Hana, Maione, Anna G., Septiadi, Dedy, Sharma, Monita, Haeni, Laetitia, Balog, Sandor, O'Connell, Olivia, Jackson, George R., Brown, David, Clippinger, Amy J., Hayden, Patrick, Petri-Fink, A

Journal:

Year:

2020

Language:

english

File:

PDF, 2.31 MB

english, 2020

13

Advancing Risk Analysis for Nanoscale Materials: Report from an International Workshop on the Role of Alternative Testing Strategies for Advancement

Shatkin, J. A., Ong, Kimberly J., Beaudrie, Christian, Clippinger, Amy J., Hendren, Christine Ogilvie, Haber, Lynne T., Hill, Myriam, Holden, Patricia, Kennedy, Alan J., Kim, Baram, MacDonell, Margare

Journal:

Year:

2016

Language:

english

File:

PDF, 399 KB

english, 2016

14

Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report

Clippinger, Amy J., Allen, David, Jarabek, Annie M., Corvaro, Marco, Gaça, Marianna, Gehen, Sean, Hotchkiss, Jon A., Patlewicz, Grace, Melbourne, Jodie, Hinderliter, Paul, Yoon, Miyoung, Huh, Dan, Low

Journal:

Toxicology in Vitro

Year:

2017

Language:

english

File:

PDF, 5.24 MB

english, 2017

15

Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity

Clippinger, Amy J., Allen, David, Behrsing, Holger, BéruBé, Kelly A., Bolger, Michael B., Casey, Warren, DeLorme, Michael, Gaça, Marianna, Gehen, Sean C., Glover, Kyle, Hayden, Patrick, Hinderliter, P

Journal:

Toxicology in Vitro

Year:

2018

Language:

english

File:

PDF, 1.32 MB

english, 2018

16

Modern affinity reagents: Recombinant antibodies and aptamers

Groff, Katherine, Brown, Jeffrey, Clippinger, Amy J.

Journal:

Biotechnology Advances

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

17

Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions

Rutherford, Nicola J., Lewis, Jada, Clippinger, Amy K., Thomas, Michael A., Adamson, Jennifer, Cruz, Pedro E., Cannon, Ashley, Xu, Guilian, Golde, Todd E., Shaw, Gerry, Borchelt, David R., Giasson, Be

Journal:

Year:

2013

Language:

english

File:

PDF, 9.44 MB

english, 2013

18

Nanomaterial Categorization for Assessing Risk Potential To Facilitate Regulatory Decision-Making

Godwin, Hilary, Nameth, Catherine, Avery, David, Bergeson, Lynn L., Bernard, Daniel, Beryt, Elizabeth, Boyes, William, Brown, Scott, Clippinger, Amy J., Cohen, Yoram, Doa, Maria, Hendren, Christine Og

Journal:

Year:

2015

Language:

english

File:

PDF, 1.89 MB

english, 2015

19

Nonanimal Approaches to Assessing the Toxicity of Inhaled Substances: Current Progress and Future Promise

Clippinger, Amy J., Allen, David, Behrsing, Holger, Hinderliter, Paul M., Landsiedel, Robert, Reinke, Emily N., Stone, Vicki

Journal:

Applied In Vitro Toxicology

Year:

2018

Language:

english

File:

PDF, 172 KB

english, 2018

20

The C-terminal region of the hepatitis B virus X protein is essential for its stability and function

Rebecca A. Lizzano, Bei Yang, Amy J. Clippinger, Michael J. Bouchard

Journal:

Year:

2011

Language:

english

File:

PDF, 697 KB

english, 2011

21

Utility of models of the gastrointestinal tract for assessment of the digestion and absorption of engineered nanomaterials released from food matrices

Lefebvre, David E., Venema, Koen, Gombau, Lourdes, Valerio, Luis G., Raju, Jayadev, Bondy, Genevieve S., Bouwmeester, Hans, Singh, R. Paul, Clippinger, Amy J., Collnot, Eva-Maria, Mehta, Rekha, Stone,

Journal:

Year:

2015

Language:

english

File:

PDF, 575 KB

english, 2015

22

Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials

Clippinger, Amy J., Ahluwalia, Arti, Allen, David, Bonner, James C., Casey, Warren, Castranova, Vincent, David, Raymond M., Halappanavar, Sabina, Hotchkiss, Jon A., Jarabek, Annie M., Maier, Monika, P

Journal:

Archives of Toxicology

Year:

2016

Language:

english

File:

PDF, 679 KB

english, 2016

23

Application of In Silico and In Vitro Approaches to Assess the Toxicity of Inhaled Substances

Clippinger, Amy J.

Journal:

Applied In Vitro Toxicology

Year:

2018

Language:

english

File:

PDF, 31 KB

english, 2018

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